The only other possible time-saver I can think of for Nancy Drew: Secrets Can Kill Remastered is the library route. The current route says that you visit the library twice. On trip one, you see the kanji book and the steroid magazine. On trip two, you use the catalogue to trigger the Jake seat puzzle, then you solve the Jake seat puzzle.
On your first trip, it's possible to do the catalogue, then turn left and do the kanji book and steroid magazine. That way, on your second trip, you can zoom up the stairs straight to the Jake seat puzzle.
There are two ways to get to the catalogue. Go forward between the desks, then take a right and head to the computers. Or you can go right, past the desks, then forward to the catalogues. I'm not doing a good job of explaining it, because I only did it the one time, but it lets you take one step forward, as opposed to two. Therefore, slightly faster.